- November 4, 1979 - January 20, 1981: Iranians seize the U.S. Embassy in Tehran, holding 52 Americans hostage for 444 days.
- December 7, 1979: Assassination of Shahriar Shafiq, nephew of the former Shah, by Iranian agents.
- July 22, 1980: Assassination of Ali Akbar Tabatabaei, former Iranian diplomat and dissident.
- April 18, 1983: Suicide bombing at the U.S. Embassy by Iranian-backed Islamic Jihad (Hezbollah precursor), killing 63 including 17 Americans.
- October 23, 1983: Truck bombing of U.S. Marine barracks by Hezbollah, killing 241 U.S. service members.
- October 23, 1983: Truck bombing of French military barracks by Hezbollah, killing 58 French paratroopers.
- December 12, 1983: Bombing of U.S. Embassy by Hezbollah, killing 5 and injuring 80.
- March 16, 1984: Kidnapping and killing of CIA station chief William Buckley by Islamic Jihad.
- September 20, 1984: Bombing of U.S. Embassy annex by Hezbollah, killing 24 including 2 U.S. military personnel.
- December 3, 1984: Hijacking of Kuwait Airways Flight 221 by Hezbollah, killing 2 U.S. officials.
- June 14, 1985: Hijacking of TWA Flight 847 by Hezbollah, killing U.S. Navy diver Robert Stethem.
- December 27, 1985: Coordinated attacks on Rome and Vienna airports by Abu Nidal group with Iranian training, killing 20 including 5 Americans and injuring over 100.
- December 1985 - September 1986: 13 bombings in Paris by group with Iranian involvement, killing 20 civilians and injuring 255.
- April 5, 1986: Bombing of La Belle Discotheque, killing 3 including 1 U.S. soldier and injuring nearly 200.
- July 18, 1987: Car bombing injuring Amirhussein Amir Parvis, former Iranian minister.
- December 21, 1988: Bombing of Pan Am Flight 103 with Iranian involvement, killing 270 including 189 Americans.
- July 13, 1989: Assassination of Abdul Rahman Ghassemlou, KDPI leader, killing 1.
- July 1989: Kidnapping and killing of U.S. Marine Col. William Higgins by Hezbollah.
- April 24, 1990: Assassination of Kazem Rajavi, MEK spokesperson.
- August 6, 1991: Assassination of Shapour Bakhtiar, former Iranian prime minister, also killing his secretary.
- March 17, 1992: Suicide bombing at Israeli Embassy by Islamic Jihad (Hezbollah-linked), killing 29 and wounding 242.
- September 17, 1992: Assassination of four Iranian Kurdish dissidents, killing 4.
- July 18, 1994: Bombing of Argentine-Israeli Mutual Association by Hezbollah with Iranian support, killing 85 and wounding over 300.
- January-May 1996: Assassinations of five Iranian exiles (two in Turkey, two in Pakistan, one in Baghdad), killing 5.
- June 25, 1996: Khobar Towers bombing by Iranian-backed Hezbollah al-Hejaz, killing 19 U.S. service members and injuring 498.
- August 7, 1998: Bombings of U.S. Embassies in Kenya and Tanzania by Iranian-backed al Qaeda with Hezbollah assistance, killing 224 including 12 Americans and injuring over 4,000.
- September 11, 2001: Iran facilitates al Qaeda transit before attacks that killed 2,977 including nearly all Americans.
- 2003-2011: Iranian-backed militias kill at least 603 U.S. troops in Iraq using EFPs and IEDs.
- January 20, 2007: IRGC Quds Force raid on U.S. facility, killing 5 U.S. soldiers.
- 2009: Iranian Cyber Army DDoS attacks on opposition and foreign sites, causing widespread disruption.
- 2012: Shamoon cyber attack on Saudi Aramco, wiping 30,000 computers and causing billions in economic harm.
- 2012-2013: Operation Ababil DDoS attacks on 46 U.S. financial institutions, locking out customers and costing billions in enhanced defenses.
- March 2015 onward:
- Iranian-backed Houthi cross-border attacks into Saudi Arabia, including missile strikes killing dozens of Saudi soldiers and civilians over years.
- June 12, 2019: Houthi drone attack on Abqaiq oil facility in Saudi Arabia, halting half of Saudi oil production temporarily, no casualties but massive economic impact.
- January 17, 2022: Houthi drone and missile attack on UAE oil facilities, killing 3 civilians and injuring 6.
- March 25, 2022: Houthi missile attack on Saudi Aramco facility in Jeddah, causing fire but no casualties.
- October 19, 2023 onward: Houthi missile and drone attacks on Israel, causing injuries and damage in southern Israel.
- November 19, 2023: Houthi hijacking of Galaxy Leader ship, holding 25 crew hostage.
- November 2023 onward: Houthi attacks on commercial shipping in Red Sea, damaging over 30 vessels, killing at least 4 crew members, injuring dozens, and disrupting global trade costing billions.
- March 6, 2024: Houthi missile attack on True Confidence ship, killing 3 crew members.
- June 12, 2024: Houthi attack on Tutor ship, sinking it and killing 1 crew member.
- October 17, 2023 - November 19, 2024: Over 180 attacks on U.S. forces in Middle East by Iran and proxies, killing 3 and wounding over 180.
- December 2023: Drone attack on U.S. forces by Iranian-backed militia, wounding 3.
- January 28, 2024: Drone attack by Kataib Hezbollah kills 3 U.S. soldiers and wounds over 40.
- November 2023 onward: Iranian-linked CyberAv3ngers attacks on U.S. water systems, causing operational disruptions.
- March 13, 2026: Iranian missile strikes on Israel, causing minor injuries and property damage.
- March 15, 2026: Iranian Sejjil ballistic missile attack on Israel.
- March 16, 2026: Iranian cluster missile strikes on Israel, injuring at least 8.
- February 28, 2026 onward: In retaliation to U.S.-Israeli strikes, Iran launches missiles at Israel (killing 9 civilians) and U.S. bases in Gulf states, hitting civilian sites in UAE, Kuwait, Saudi Arabia, Bahrain, Qatar, Oman, Jordan, and Iraq; ongoing exchanges cause over 1,800 deaths including civilians and U.S./French troops.
