Am I talking about an actual secession or the threat of a secession?
Can you understand that what is needed is a confrontation with the federal government which is what a state threatening to secede will automatically create. There are two important things to consider here,
1. A world stage for the state threatening to secede so it can voice it's grievances against the fed and more importantly,
2, The fed being forced to explain why the state has no right to secede. The fed will then have to answer this very important question before the world. Why does part of your country wish to leave? It will be the fed and the fed alone that will be put on trial before the world's civilized countries and not the threatening to secede state. And that is the whole point, a creation of a constitutional crisis.
For as many legal angles the fed will use along with trying to intimidate the citizens of the state with it's justice Department and the IRS and it's legion of lawyers, the state will counter with it's own army of lawyers defending it and it's citizens.