LET US NOT FORGET THE BIG PICTURE HERE. We and the world spent 2 - 2 1/2 months going down TRUMP'S rabbit hole. MORE TIME LOST!
Day 2 after Trump started TOUTING his snake oil theory, this amateur posted the contraindications of his CHOSEN drug right out of the PDR. I stated that was a shitload of contraindications on a 60 year old drug and I NOTED at the time people with HEART DISEASE, DIABETES and alcoholism--active or sober--were major groups which could be precluded from using it. AND that represented a shitload of the US population. My instincts were dead on (no pun intended). Heart arrhythmias lead to sudden heart attacks and STROKES. Surely you have seen the ads. Seems a pretty important 'side effect' to me.
They didn't have the luxury of a double blind study. But HONEST #'s like this don't lie. Of course I guess 6 continents and all the medical institutions could have 'colluded' to change medical records and numbers. Sure! That'll be the next conspiracy theory. Stay tuned...
“It’s one thing not to have benefit, but this shows distinct harm,”
Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says
An analysis of 96,000 patients shows those treated with hydroxychloroquine were also more likely to suffer irregular heart rhythms
President Trump on May 18 said that he has been taking the anti-malarial drug hydroxychloroquine as a preventive measure against the coronavirus. (The Washington Post)
By Ariana Eunjung Cha and
Laurie McGinley
May 22, 2020 at 8:28 a.m. EDT
The Washington Post is providing this important information about the coronavirus for free. For more free coverage of the coronavirus pandemic, sign up for our daily Coronavirus Updates newsletter where all stories are free to read.
A study of 96,000 hospitalized coronavirus patients on six continents found that those who received an antimalarial drug promoted by President Trump as a “game changer” in the fight against the virus had a significantly higher risk of death compared with those who did not.
People treated with hydroxychloroquine, or the closely related drug chloroquine, were also more likely to develop a type of irregular heart rhythm, or arrhythmia, that can lead to sudden cardiac death, it concluded.
The study, published Friday in the medical journal the Lancet, is the largest analysis to date of the risks and benefits of treating covid-19 patients with antimalarial drugs. It is based on a retrospective analysis of medical records, not a controlled study in which patients are divided randomly into treatment groups — a method considered the gold standard of medicine. But the sheer size of the study was convincing to some scientists.
“It’s one thing not to have benefit, but this shows distinct harm,” said Eric Topol, a cardiologist and director of the Scripps Research Translational Institute. “If there was ever hope for this drug, this is the death of it.”
David Maron, director of preventive cardiology at the Stanford University School of Medicine, said that “these findings provide absolutely no reason for optimism that these drugs might be useful in the prevention or treatment of covid-19.”
Past studies also found scant or no evidence of hydroxychloroquine’s benefit in treating sick patients, while reports mounted of dangerous heart problems associated with its use. As a result, the Food and Drug Administration last month warned against the use of the drug outside hospital settings or clinical trials
The new analysis — by Mandeep Mehra, a Harvard Medical School professor and physician at Brigham and Women’s Hospital, and colleagues at other institutions — included patients with a positive laboratory test for covid-19 who were hospitalized between Dec. 20, 2019, and April 14, 2020, at 671 medical centers worldwide. The mean age was 54 years, and 53 percent were men. Those who were on mechanical ventilators or who received remdesivir, an antiviral drug made by Gilead Sciences that has shown promise in decreasing recovery times, were excluded.
Mehra said in an interview that the widespread use of antimalarials for covid-19 patients was based on the idea of “a desperate disease demands desperate measures," but that we have learned a hard lesson from the experience about the importance of first doing no harm.
In retrospect, Mehra said, using the drugs without systematic testing was “unwise.”
“I wish we had had this information at the outset,” he said, “as there has potentially been harm to patients.”
Nearly 15,000 of the 96,000 patients in the analysis were treated with hydroxychloroquine or chloroquine alone or in combination with a type of antibiotics known as a macrolide, such as azithromycin or clarithromycin, within 48 hours of their diagnosis.
The difference between patients who received the antimalarials and those who did not was striking.
For those given hydroxychloroquine, there was a 34 percent increase in risk of mortality and a 137 percent increased risk of a serious heart arrhythmias. For those receiving hydroxychloroquine and an antibiotic — the cocktail endorsed by Trump — there was a 45 percent increased risk of death and a 411 percent increased risk of serious heart arrhythmias...
https://www.washingtonpost.com/healt...navirus-study/
Last edited by Centerleftfl; 05-22-2020 at 08:45 AM.
WK1 3/28-/4 _Cases 301k--Dead 18.1k Lethality 2.72%
WK2 4/5-/13 _Cases 555k--Dead 22.1K Lethality 3.9%
WK3 4/20-/21 Cases 774k -Dead 37.2K Lethality 4.8%
WK4 4/22-/29 Cases 1M --Dead 58.8K Lethality 5.9%
WK5 5/1-/8__ Cases 1.3M -Dead 75.7K Lethality 6.1%
WK6 5/9-16__Cases 1.4M --Dead 85.8K Lethality 6.1%
WK7 5/17-24_Cases 1.7M - Dead 97.6K Lethality 5.9%
WK8 5/28 Cases 1.7M - DEAD 101.2K - Same
Guno צְבִי (05-23-2020), PoliTalker (05-22-2020), Trumpet (05-22-2020)
The president used the drug, temporally, with the approval of the White House doctor.
He did not encourage others to use it.
Try to think for yourself, Snowflake. Use it, don't use it.
Choice.
Stretch (05-22-2020)
This was being said all along by the medical experts. But of course Trump and his cult refused to listen, and instead claimed that 'the left' wanted to cast doubt on a drug that was proven effective. Now we know better. I'm sure the cult will now wait for their instructions as to how they discredit the study, the person behind the study, and anyone who believes the study. Because they would rather be lied to than have to deal with the cognitive dissonance.
Earl (05-22-2020)
PoliTalker (05-22-2020), Trumpet (05-22-2020)
The president used the drug, temporally, with the approval of the White House doctor.
He did not encourage others to use it.
Try to think for yourself, Snowflakes. Use it, don't use it.
Choice.
Stretch (05-22-2020)
Earl (05-22-2020)
Hydroxychloroquine Has about 90 Percent Chance of Helping COVID-19 Patients
"In a letter to Gov. Doug Ducey of Arizona, the Association of American Physicians and Surgeons (AAPS) presents a frequently updated table of studies that report results of treating COVID-19 with the anti-malaria drugs chloroquine (CQ) and hydroxychloroquine (HCQ, Plaquenil®).
To date, the total number of reported patients treated with HCQ, with or without zinc and the widely used antibiotic azithromycin, is 2,333, writes AAPS, in observational data from China, France, South Korea, Algeria, and the U.S. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.
The antiviral properties of these drugs have been studied since 2003. Particularly when combined with zinc, they hinder viral entry into cells and inhibit replication. They may also prevent overreaction by the immune system, which causes the cytokine storm responsible for much of the damage in severe cases, explains AAPS. HCQ is often very helpful in treating autoimmune diseases such as lupus and rheumatoid arthritis.
Additional benefits shown in some studies, AAPS states, is to decrease the number of days when a patient is contagious, reduce the need for ventilators, and shorten the time to clinical recovery.
Peer-reviewed studies published from January through April 20, 2020, provide clear and convincing evidence that HCQ may be beneficial in COVID-19, especially when used early, states AAPS. Unfortunately, although it is perfectly legal to prescribe drugs for new indications not on the label, the Food and Drug Administration (FDA) has recommended that CQ and HCQ should be used for COVID-19 only in hospitalized patients in the setting of a clinical study if available. Most states are making it difficult for physicians to prescribe or pharmacists to dispense these medications.
As the letter to Gov. Ducey notes, “Many nations, including Turkey and India, are protecting medical workers and contacts of infected persons prophylactically. According to worldometers.info, deaths per million persons from COVID-19 as of Apr 27 are 167 in the U.S., 33 in Turkey, and 0.6 in India.”
After Morocco and Algeria began using HCQ, a trend break and sharp reduction in their COVID-19 case fatality rate occurred.
Vaccines and results of randomized double-blind controlled trials of new drugs are at best months away. But patients are dying now, while affordable, long-used drugs would be available except for government restrictions, AAPS states.
The Association of American Physicians and Surgeons (AAPS) has represented physicians of all specialties in all states since 1943. The AAPS motto is omnia pro aegroto, meaning everything for the patient."
aaps,com
Earl (05-22-2020)
Large study finds hydroxychloroquine Covid-19 treatments linked to greater risk of death and heart arrhythmia
Seriously ill Covid-19 patients who were treated with hydroxychloroquine and chloroquine were more likely to die or develop dangerous heart arrhythmias, according to a large observational study published Friday in the medical journal The Lancet.
https://www.cnn.com/us/live-news/us-...0c916b21bc0959
Earl (05-22-2020)
PoliTalker (05-22-2020)
Stretch (05-23-2020)
I suppose you could say the same thing about Bleach!
You can drink it- or not drink it!
Choice is great isn't it?
If you don't want an abortion- Don't have one!
You don't want Obamacare- Don't buy it!
You don't want to mail in your vote- Go stand in line or just don't vote.
But you need to be consistent with your idea about choice- Is seems you are selective about who you want to have choices and as to what choices you want people to have.
That's pretty much Trumptarded mentality- IF YOU ASK ME!
And if you didn't ask me- I am so very glad to have volunteered this great advice to you! LOL!
Earl (05-22-2020)
Althea (05-22-2020), AProudLefty (05-22-2020), Trumpet (05-22-2020)
WK1 3/28-/4 _Cases 301k--Dead 18.1k Lethality 2.72%
WK2 4/5-/13 _Cases 555k--Dead 22.1K Lethality 3.9%
WK3 4/20-/21 Cases 774k -Dead 37.2K Lethality 4.8%
WK4 4/22-/29 Cases 1M --Dead 58.8K Lethality 5.9%
WK5 5/1-/8__ Cases 1.3M -Dead 75.7K Lethality 6.1%
WK6 5/9-16__Cases 1.4M --Dead 85.8K Lethality 6.1%
WK7 5/17-24_Cases 1.7M - Dead 97.6K Lethality 5.9%
WK8 5/28 Cases 1.7M - DEAD 101.2K - Same
Earl (05-22-2020)
Hydroxychloroquine Has about 90 Percent Chance of Helping COVID-19 Patients
"In a letter to Gov. Doug Ducey of Arizona, the Association of American Physicians and Surgeons (AAPS) presents a frequently updated table of studies that report results of treating COVID-19 with the anti-malaria drugs chloroquine (CQ) and hydroxychloroquine (HCQ, Plaquenil®).
To date, the total number of reported patients treated with HCQ, with or without zinc and the widely used antibiotic azithromycin, is 2,333, writes AAPS, in observational data from China, France, South Korea, Algeria, and the U.S. Of these, 2,137 or 91.6 percent improved clinically. There were 63 deaths, all but 11 in a single retrospective report from the Veterans Administration where the patients were severely ill.
The antiviral properties of these drugs have been studied since 2003. Particularly when combined with zinc, they hinder viral entry into cells and inhibit replication. They may also prevent overreaction by the immune system, which causes the cytokine storm responsible for much of the damage in severe cases, explains AAPS. HCQ is often very helpful in treating autoimmune diseases such as lupus and rheumatoid arthritis.
Additional benefits shown in some studies, AAPS states, is to decrease the number of days when a patient is contagious, reduce the need for ventilators, and shorten the time to clinical recovery.
Peer-reviewed studies published from January through April 20, 2020, provide clear and convincing evidence that HCQ may be beneficial in COVID-19, especially when used early, states AAPS. Unfortunately, although it is perfectly legal to prescribe drugs for new indications not on the label, the Food and Drug Administration (FDA) has recommended that CQ and HCQ should be used for COVID-19 only in hospitalized patients in the setting of a clinical study if available. Most states are making it difficult for physicians to prescribe or pharmacists to dispense these medications.
As the letter to Gov. Ducey notes, “Many nations, including Turkey and India, are protecting medical workers and contacts of infected persons prophylactically. According to worldometers.info, deaths per million persons from COVID-19 as of Apr 27 are 167 in the U.S., 33 in Turkey, and 0.6 in India.”
After Morocco and Algeria began using HCQ, a trend break and sharp reduction in their COVID-19 case fatality rate occurred.
Vaccines and results of randomized double-blind controlled trials of new drugs are at best months away. But patients are dying now, while affordable, long-used drugs would be available except for government restrictions, AAPS states.
The Association of American Physicians and Surgeons (AAPS) has represented physicians of all specialties in all states since 1943. The AAPS motto is omnia pro aegroto, meaning everything for the patient."
aaps,com
Nordberg (05-23-2020)
Bookmarks